https://www.journalsmededu.pl/index.php/OncoReview/issue/feed OncoReview 2021-03-03T15:40:11+01:00 Marcin Kuzma marcin@journalsmededu.pl Open Journal Systems <p>The main area of <em>OncoReview’s </em>&nbsp;scientific mission is the emerging field of interdisciplinary oncology, with particular emphasis on cardio-oncology. Scientific papers published in the journal concern modern diagnostic and therapeutic methods used in this population of patients, as well as all adverse events related to anticancer treatment. Objective assessment of the benefits and risks of new oncological drugs is a unique benefit of the published works.&nbsp;<br><span lang="en-GB"><br></span><span lang="en-GB"><strong>e-ISSN: </strong>2450-6125&nbsp; <strong>&nbsp; &nbsp; &nbsp; DOI: </strong>10.24292/01.OR<br><br><strong>Indexed in:&nbsp;</strong></span><strong>SCOPUS</strong>: SJR 2019 = 0.125; SNIP 2019= 0.099<br><span lang="en-GB">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Polish Journals Master List:&nbsp;<strong>20 points</strong>&nbsp;<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Index Copernicus: 116.25&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Google Scholar<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Polish Medical Bibliography</span></p> <p>&nbsp;</p> https://www.journalsmededu.pl/index.php/OncoReview/article/view/1147 Stereotactic management of arrhythmia – radiosurgery in treatment of ventricular tachycardia (SMART-VT) – clinical trial protocol and study rationale 2021-02-18T14:19:16+01:00 Marcin Miszczyk dd@mededu.pl Tomasz Jadczyk cd@mededu.pl Bartłomiej Tomasik ff@mededu.pl Tomasz Latusek dd2@mk.pl Jacek Bednarek ff@mededu.pl Radosław Kurzelowski dd@mededu.pl Krzysztof Gołba ff@me.pl Wojciech Wojakowski ff@dd.pl Krystian Wita fr@dh.pl Łukasz Dolla sd@sdf.pl Aleksandra Grządziel rgf@dj.pl Sławomir Blamek slawomir.blamek@io.gliwice.pl <p>Patients with ventricular tachycardia are usually treated with antiarrhythmic drugs and ablation if the arrhythmia substrate is available for invasive treatment. Despite high efficiency of this treatment there is a significant group of patients who do not benefit from available treatment methods, either because they cannot be applied or do not allow for durable control of the disease. For that reason a novel treatment method, STereotactic Arrhythmia Radioablation (STAR) has been proposed and its safety and efficiency is extensively studied throughout the world. The method is based on irradiation of the arrhythmia substrate identified with electrophysiological examination with high-precision image-guided radiosurgical methods usually used for ablation of malignant tumors. Here we present the protocol of the first Polish study on STAR in patients with intractable ventricular tachycardia (STARVT, NCT04642963), designed to test the safety of the method. Secondary endpoints include measures of the treatment efficiency.</p> 2021-02-14T00:00:00+01:00 Copyright (c) 2021 Medical Education https://www.journalsmededu.pl/index.php/OncoReview/article/view/1106 The oncological treatment and cardiotoxicity problem – the role of biomarkers 2021-02-17T17:06:06+01:00 Magdalena Dudek magdalena.dudek@skpp.edu.pl Marta Kałużna-Oleksy mededu@mededu.pl Jacek Migaj mededu@mededu.pl Maciej Lesiak mededu@mededu.pl Ewa Straburzyńska-Migaj mededu@mededu.pl <p>Cancer and cardiovascular diseases are a leading causes of morbidity and mortality in developed countries. Cardiological complications of oncological treatment are a significant problem that can be manifested in both permanent and transient cardiac dysfunction including myocardial damage, left ventricular dysfunction, and heart failure, hypertension, ischemia, as well as arrhythmias or QT prolongation, which can be life-threatening. Early detection of cardiotoxicity due to cancer treatment is crucial in the prevention of adverse cardiovascular outcomes in this group of patients. In this review we try to summarize the role of biomarkers in the detection of cardiotoxicity due to cancer treatment.</p> 2020-12-04T00:00:00+01:00 Copyright (c) 2020 Medical Education https://www.journalsmededu.pl/index.php/OncoReview/article/view/1143 Cancer-related microagiopathic hemolytic anemia in a patient with breast cancer – diagnostic difficulties 2021-02-17T17:06:04+01:00 Kamila Skwierawska kskwierawska@o2.pl Krzysztof Woźniak dd@mededu.pl Anna Waszczuk-Gajda med@mededu.pl Joanna Drozd-Sokołowska dd@mededu.pl Piotr Kacprzyk ssf@mededu.pl Marita Rachid Chehab ee@mededu.pl Piotr Boguradzki dd@mededu.pl Wiesław Wiktor Jędrzejczak ww@mededu.pl Grzegorz Władysław Basak dd@mededu.pl <p>&nbsp;Cancer-related microangiopathic hemolytic anemia is rarely recognized as a paraneoplastic syndrome with a very poor prognosis in cancer patients. The treatment and prognosis are significantly different from that in other thrombotic microangiopathies, such as thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. The case of described patient demonstrates the diagnostic difficulties in diagnosing the causes of hemolytic anemia in patient with breast cancer and appropriate treatment.</p> 2020-12-31T00:00:00+01:00 Copyright (c) 2020 Medical Education https://www.journalsmededu.pl/index.php/OncoReview/article/view/1145 Monoclonal gammopathy of renal significance – diagnostic and therapeutic problems 2021-02-18T11:19:39+01:00 Grzegorz Kade grzegorz.kade@poliklinika.net Sebastian Spaleniak ff@mededu.pl Janusz Hałka dd@mededu.pl Stefan Antosiewicz dd@mededu.pl <p>The term <em>monoclonal gammopathy of renal significance</em> MGRS means a group of renal diseases resulting from the presence of the monoclonal protein produced by plasmatic cells or other clones of B cells. The patients with MGRS do not fulfill the diagnostics criteria both of multiple myeloma and other neoplasm originating from B cells. The involvement of different renal structures in the course of MGRS results the dysfunction of kidneys. The monoclonal protein may injure the glomerular structures (including vascular) as well as tubular structures (interstitial in more wide sense). The early diagnosis of MGRS is difficult and the late detection of the disease is connected with high risk of irreversible renal damage. Therefore, the multidisciplinary cooperation – including general practitioners, nephrologists, hematologists and nephro-pathologists – is particularly important for the diagnostics and treatment of MGRS cases. This new hemato-nephrological meta-disease entity is connected with relatively high morbidity and mortality as well as relapses in transplanted kidney. The decision of the treatment initiation against the toxic clone in MGRS cases results mainly from the nephrological reasons. The article presents current diagnostic and therapeutic possibilities that may be used in MGRS patients. The main purpose of this article was to present the current state of knowledge regarding the diagnostics and treatment of MGRS.</p> 2021-02-04T00:00:00+01:00 Copyright (c) 2021 Medical Education https://www.journalsmededu.pl/index.php/OncoReview/article/view/1146 Cancer pain as a meaningful aspect of the oncological treatment 2021-03-03T15:40:11+01:00 Izabela Marzec dd@mededu.pl Kinga Grabska ff@mededu.pl Marta M. Fudalej mmfudalej@gmail.com Anna M. Badowska-Kozakiewicz ff@mededu.pl <p><strong>Introduction and objective</strong>: Pain is the most common and universal symptom among all patients with the oncological disease. Pain significantly reduces the quality of life, hinders decent functioning, and plays a significant role in the deterioration of the mental health of the patient and his close relatives. The study aimed to discuss the mainstreaming of effective pain treatment and to review various assessments and scales (including Brief Pain Inventory, Illness Perception Questionnaire and Numeric Rating Scale) concerning the psychological aspect of pain in selected neoplastic diseases.State of knowledge: We can distinguish various treatments for pain that can be divided into pharmacological and non-pharmacological methods. Latest studies revealed that pain treatment appears to be more and more meaningful. Various factors might influence pain perception and response to the applied treatment. Among all malignancies, special attention is paid to the pain issue in following cancers: colon cancer, gastric cancer, pancreatic cancer, ovarian cancer, breast cancer and lung cancer, that were described in this paper.<br><strong>Conclusions</strong>: Effective pain relief presents a positive effect, both on the physical and mental state of the patient. It also helps to maintain calm mental health among relatives. Nowadays, integration of the best methods for pain relief that are characterized as humanitarian, easily accessible and effective, seems to be one of the biggest challenges for both oncological and palliative health workers.</p> 2021-01-10T00:00:00+01:00 Copyright (c) 2021 Medical Education