OphthaTherapy. Therapies in Ophthalmology https://www.journalsmededu.pl/index.php/ophthatherapy <p>"OphthaTherapy. Therapies in Ophthalmology" (abbr.: OphthaTherapy) is a peer-reviewed scientific quarterly publishing papers in: ophthalmology, ophthalmic surgery (including minimally invasive surgery and laser therapy), pharmacological treatment of eye diseases, including glaucoma, as well as work in the contactology. The journal is on the list of the Polish Ministry of Science and Higher Education. For publishing the article, the author receives 20 points.<br>We encourage you to submit: original papers, review articles, case reports, rapid communication, research letters, hypotheses, meeting proceedings, letter to the editor. There are no submission or processing charges.</p> <p><strong>"OphthaTherapy" accepts submissions in English only. Other language versions may be published as additional ones.</strong><br><br><strong><span lang="en-GB">e-ISSN: </span></strong><span lang="en-GB">2543-9987</span><span lang="en-GB">&nbsp;</span><strong><span lang="en-GB"> &nbsp; &nbsp; &nbsp;ISSN: 2353-7175 &nbsp; &nbsp; &nbsp; DOI: </span></strong><span lang="en-GB">10.24292/01.OT<br><br></span><strong><span lang="en-GB">Indexed in:&nbsp;</span></strong><span lang="en-GB">Polish Journals Master List: <strong>20 points<br></strong>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;Index Copernicus:<strong><strong class="ng-binding">72.79</strong></strong><br></span><span lang="en-GB">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;Google Scholar<br></span>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Polish Scientific Journal Database<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; ARIANTA<br>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; WorldCat</p> Medical Education sp. z o.o. en-US OphthaTherapy. Therapies in Ophthalmology 2353-7175 <p><strong>Copyright: © Medical Education sp. z o.o.</strong> License allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.</p> <p><em>Address reprint requests to: Medical Education, Marcin Kuźma (<a href="mailto:marcin.kuzma@mededu.pl">marcin.kuzma@mededu.pl</a>)</em></p> Change in corneal astigmatism with age https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/1755 <p>The work is theoretical in nature and was created to test the relationship between age and changes in astigmatism. The analysis was carried out on the basis of the available studies described in the literature on the subject. The collected statistical data and medical information allow for the conclusion that astigmatism may change with age. The implemented project presents results that have both cognitive and application value. The identified bindings can be used in the medical practice of patients with astigmatism.</p> Małgorzata Gawlak Kinga Czarnacka Alicja Chmura Ada Pandey Justyna Gugnowska Angelika Kruszyńska Oliwia Cwalina Katarzyna Sajak-Hydzik Ilona Pawlicka Maciej Kozak Copyright (c) 2022 Medical Education sp. z o.o. https://creativecommons.org/licenses/by-nc-nd/4.0 2022-06-30 2022-06-30 9 2 85 89 10.24292/01.OT.250622 Kappa and alpha angles in preoperative diagnostics of hyperopic patients qualified for multifocal lens implantation using iTrace analyser https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/1724 <p>The value and location of angles alpha (α) and kappa (κ) in the eyes diagnosed with hyperopia, qualified for premium class lens implantation were subject to evaluation. 67 patients, 101 eyes with hyperopia ranging from +0.5 Dsph to +10.62 Dsph were included into the study. For both angles, α and κ, their most common location is in the inferior temporal quadrant, followed by the superior temporal quadrant. A statistically significant correlation was observed between the value of angles α and κ and the range of hyperopia. In each case the angle value was examined using the iTrace<sup>TM</sup> analyser.</p> Adam Cywiński Olaf Szyja Copyright (c) 2022 Medical Education sp. z o.o. https://creativecommons.org/licenses/by-nc-nd/4.0 2022-06-30 2022-06-30 9 2 90 97 10.24292/01.OT.010622 Factors affecting the course of Graves’ Orbitopathy and poor response to glucocorticoid treatment followed by orbital radiotherapy https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/1783 <p>Graves’ orbitopathy is a rare autoimmune disorder characterized by the inflammation of orbital tissues. The course of disease can be described in terms of its activity and severity.</p> <p><strong>Aim</strong>: The aim of our study was to determine the factors affecting the activity and severity of Graves’ orbitopathy, as well as to identify the predictive factors of poor response to glucocorticoid treatment followed by orbital irradiation.</p> <p><strong>Methods</strong>: We performed a prospective observational study of 214 patients with Graves’ orbitopathy who were divided into two groups depending on the treatment they had previously obtained for their Graves’ disease. They received i.v. methylprednisolone pulses followed by orbital radiotherapy. They were examined and had their TSH, TRAb and FT<sub>4</sub> levels evaluated prior to treatment and after 1, 6 and 12 months.</p> <p><strong>Results</strong>: A pre-treatment TRAb concentration higher by one unit (U/L) implied a mean increase in the relative risk of active orbitopathy by 4.7% (p = 0.0362). A TRAb concentration higher by one U/L 1 month after treatment implied a mean increase in the relative risk of moderate-to-severe and severe GO by 8.7% (p = 0.0167) 6 months after treatment. As regards poor response to treatment, patients with moderate-to-severe and severe Graves’ orbitopathy on admission carried a higher risk of being non-responders. Each point scored on the NOSPECS scale prior to treatment increased the relative risk of the patient being a non-responder by 30%.</p> <p><strong>Conclusions</strong>: Patients with higher TRAb levels have a higher risk of active Graves’ orbitopathy and moderate-to-severe and severe Graves’ orbitopathy. Monitoring TRAb serum concentration in those patients is of great importance. Patients with more severe Graves’ orbitopathy carry a higher risk of being poor responders to immunosuppressive treatment. Therefore, careful monitoring of patients with Graves’ orbitopathy and their early referral to specialized centers is essential.</p> Agnieszka Jagiełło-Korzeniowska Andrzej Sokołowski Alicja Hubalewska-Dydejczyk Bożena Romanowska-Dixon Agata Bałdys-Waligórska Copyright (c) 2022 Medical Education sp. z o.o. https://creativecommons.org/licenses/by-nc-nd/4.0 2022-05-19 2022-05-19 9 2 98 105 10.24292/01.OT.190522 Bilateral anterior lenticonus in the course of Alport syndrome – a case report https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/1914 <p>Alport syndrome is a genetic disease that leads not only to chronic kidney disease but also to loss of hearing and vison. The article presents a case of a 34-year-old with anterior lenticonus in Alport syndrome. Due to the progressive deterioration of vision and the ineffectiveness of the selection of glasses, he was qualified for the surgery – the phacoemulsification for immature cataract of distorted lenses.</p> Ada Pandey Justyna Gugnowska Angelika Kruszyńska Oliwia Cwalina Kinga Czarnacka Małgorzata Gawlak Alicja Chmura Maciej Kozak Katarzyna Sajak-Hydzik Ilona Pawlicka Copyright (c) 2022-06-30 2022-06-30 9 2 107 116 10.24292/01.OT.070622 Rational therapy of ocular surface bacterial infections with fluoroquinolones https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/1915 <p>There are many mechanisms, that protect healthy ocular surface from invasion of pathogenic bacteria. Infection and inflammation develop on the ocular surface in case of damaging natural defensive barrier. One of the most common ocular surface infections are bacterial conjunctivitis and keratitis. Rational therapy of these diseases should be based on antibiotics that have broad antimicrobial spectrum, good efficacy and safety. All these qualities have fluoroquinolones: ofloxacin, levofloxacin and moxifloxacin.</p> Ewelina Trojacka Justyna Izdebska Copyright (c) 2022 https://creativecommons.org/licenses/by-nc-nd/4.0 2022-06-30 2022-06-30 9 2 119 123 10.24292/01.OT.260522 Optic disc swelling in the paediatric population https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/1796 <p>Swelling of the optic disc may result from inflammation, infiltration, optic nerve compression or ischaemia, as well as increased intracranial pressure. It can be imitated by local structural features of the optic disc leading to pseudopapilloedema. Disease entities leading to optic disc swelling can take different courses in the paediatric population compared to the adult population. Investigations used to confirm diagnosis include optical coherence tomography (OCT), ocular ultrasound, fluorescein angiography, visual evoked potentials (VEP), and imaging studies of head and orbits.</p> Aleksandra Chrobak Sylwia Burza-Grycz Agnieszka Samsel Copyright (c) 2022 Medical Education sp. z o.o. https://creativecommons.org/licenses/by-nc-nd/4.0 2022-06-30 2022-06-30 9 2 126 132 10.24292/01.OT.100622 Patient with cataract – observations after 2 years of the pandemic and future prospects https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/1793 <p>Cataract is a disease in which the natural lens becomes completely or partially cloudy. During the pandemic, there was a significant decrease in the number of cataract surgeries performed compared to previous years, due to fear of the disease and the safety of the procedures performed. Cataract surgery should be performed in patients whose visual acuity deterioration has an impact on the performance of life or work activities. Due to the pandemic, some patients report to a more advanced stage of cataract, which leads to a reduction in their quality of life. Such surgery can be associated with a higher risk of surgical complications and longer recovery time. The development of new intraocular lens technologies, increased life expectancy, as well as changing lifestyles and increased activity of the elderly contribute to the increasing choice of premium intraocular lenses by patients. These lenses enable patients to achieve satisfactory uncorrected visual acuity not only for distance, but also for near and intermediate distances.</p> Marta Misiuk-Hojło Anna Dołowiec-Kwapisz Copyright (c) 2020 http://creativecommons.org/licenses/by-nc-nd/4.0/ 2022-05-11 2022-05-11 9 2 134 141 10.24292/01.OT.110522 Choosing the right surgical treatment for hyperopia https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/1794 <p>Several aspects make the treatment of hyperopia and selecting the treatment method challenging. This article has reviewed the main surgical options for hyperopia and factors that must be considered when choosing the right treatment. The modern refractive technology offers excellent options with the optimal choice of procedure being dependent on the level of refractive error, age of the patient and the unique anatomical factors in each case. Surgeons must perform a complete evaluation and risk-benefit assessment of the individual patient to select the best procedure.</p> Jan Grzeszkowiak Joanna Wierzbowska Copyright (c) 2022 Medical Education sp. z o.o. https://creativecommons.org/licenses/by-nc-nd/4.0 2022-06-30 2022-06-30 9 2 143 148 10.24292/01.OT.120622 The impact of various factors on the occurrence and type of visual experiences during the cataract surgery https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/1797 <p><strong>Aims</strong>: The aim was to check whether there is a relationship between ophthalmic and non-ophthalmic concomitant diseases and visual experiences during surgery. In addition, we wanted to verify whether visual experiences are influenced by such factors as age, gender, education, stress, etc.</p> <p><strong>Methods</strong>: The patients phoned a few days after the surgery in order to be interviewed post-operatively by a 30-question questionnaire. Questions were asked on demographic data, concomitant diseases, both ophthalmic and non-ophthalmic, emotional and visual experiences during the cataract surgery p-value was calculated from the Chi-Square Test.</p> <p><strong>Results</strong>: The study comprised 121 women and 87 men. 63.9% of patients underwent cataract surgery for the first time. Among 208 respondents 73 (35.1%) had light impressions and 77 (37%) reported visual impressions. Patients under 60 were more likely to experience both light and visual impressions (p &lt; 0.05). Particular visual defects and concomitant diseases, both ophthalmic and non-ophthalmic, can influence the type of visual experiences. Stress was positively correlated with the occurrence of both light and visual impressions (p &lt; 0.05) but it did not influence the exact type of visual experiences. For half of the respondents (51.0%), the impressions seen during the surgery were neutral. Only 14.4% of patients assessed these sensations as pleasant.</p> <p><strong>Conclusion</strong>: Patients experienced a variety of visual sensations, which are not usually unpleasant, however they occurred more often among stressed patients and could also raise the stress level. Proper preoperative counselling is needed to help patients cope with the stress before surgery.</p> Zofia Kampka Przemysław Urbaniec Emila Senderek Dorota Pojda-Wilczek Copyright (c) 2022 Medical Education sp. z o.o. https://creativecommons.org/licenses/by-nc-nd/4.0 2022-06-30 2022-06-30 9 2 151 157 10.24292/01.OT.200622