Band keratopathy – chelation or therapeutic photokeratectomy Review article
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Published:
Sep 30, 2023
Keywords:
band keratopathy, calcium deposits, EDTA chelation, phototherapeutic keratectomy, excimer laser, corneal degeneration, ethylenediaminetetraacetic acid
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Abstract
Corneal degeneration changes corneal shape and causing its translucency disappear. The division of corneal degeneration is made according to the type deposited in its layer. Among the factors causing keratopathy, the following can be mentioned: iron, collagen, hemosiderins, and calcium salts, the last ones cause band keratopathy. This feature is characteristic of the deposition of opacities in the superficial layers of the cornea. In the treatment of band keratopathy, ethylenediaminetetraacetic acid chelation and excimer laser phototherapeutic keratectomy are discussed.
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1.
Alsoubie I, Pyza A, Kaczmarek J, Czarnacka K, Prokop D, Kuźlik B, Chmura A, Pandey A, Gawlak M, Żaczek B, Sajak-Hydzik K, Pawlicka I, Piskorz A, Kozak M, Roszkowska AM. Band keratopathy – chelation or therapeutic photokeratectomy. Ophthatherapy [Internet]. 2023Sep.30 [cited 2024May9];10(3):195-9. Available from: https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/2866
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Conservative treatment
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10.Kobayashi W, Yokokura S, Hariya T et al. Two percent ethylenediaminetetraacetic acid chelation treatment for band-shaped keratopathy, without blunt scratching after removal of the corneal epithelium. Clin Ophthalmol. 2015; 9: 217-23. http://doi.org/10.2147/OPTH.S75938.
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12. Nagpal R, Maharana PK, Roop P et al. Phototherapeutic keratectomy. Surv Ophthalmol. 2020; 65(1): 79-108. http://doi.org/10.1016/j.survophthal.2019.07.002.
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14. Deshmukh R, Reddy JC, Rapuano CJ et al. Phototherapeutic keratectomy: Indications, methods and decision making. Indian J Ophthalmol. 2020; 68(12): 2856-66. http://doi.org/10.4103/ijo.IJO_1524_20.
15. Wei R, Li M, Yang W et al. Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for Retinoblastoma. Front Med (Lausanne). 2021; 8: 668762. http://doi.org/10.3389/fmed.2021.668762.
16. Qian Y, Zhao P, Li H et al. Transepithelial phototherapeutic keratectomy for the treatment of severe band keratopathy. Int Ophthalmol. 2020; 40(10): 2469-74. http://doi.org/10.1007/s10792-020-01574-3.
17. Sharma N, Mannan R, Sinha R et al. Excimer laser phototherapeutic keratectomy for the treatment of silicone oil-induced band-shaped keratopathy. Eye Contact Lens. 2011; 37(5): 282-5. http://doi.org/10.1097/ICL.0b013e31821269f1.
18. Stewart OG, Morrell AJ. Management of band keratopathy with excimer phototherapeutic keratectomy: visual, refractive, and symptomatic outcome. Eye (Lond). 2003; 17(2): 233-7. http://doi.org/10.1038/sj.eye.6700327.
19. Spadea L, Giannico MI, Iannaccone A et al. Excimer laser-assisted phototherapeutic keratectomies combined to EDTA chelation for the treatment of calcific band keratopathy. Eur J Ophthalmol. 2022; 32(1): NP42-NP46. http://doi.org/10.1177/1120672120969033.
2. Pogrzebielski A. Budowa narządu wzroku. Medycyna Praktyczna. Online (access: 30.06.2023).
3. Kwon YS, Song YS, Kim JC. New treatment for band keratopathy: superficial lamellar keratectomy, EDTA chelation and amniotic membrane transplantation. J Korean Med Sci. 2004; 19(4): 611-5. http://doi.org/10.3346/jkms.2004.19.4.611.
4. Wiedemann J, Cursiefen C. Bandkeratopathie bei ektoper Vitamin-D-Produktion bei Sarkoidose [Band keratopathy in ectopic vitamin D production in sarcoidosis]. Ophthalmologie. 2022. http://doi.org/10.1007/s00347-022-01679-3.
5. Ferda D, Mrukwa-Kominek E. Powikłania rogówkowe po zabiegu witrektomii przez pars plana. Okulistyka po Dyplomie. 2013; 3(3): 23-5.
6. Rekomendacja nr 123/2013 z dnia 16 września 2013 r. Prezesa Agencji Oceny Technologii Medycznych w sprawie zasadności wydawania zgód na refundację produktu leczniczego Ophtasiloxane (Dimethicone), krople do oczu we wskazaniach: jaskra w zaawansowanym stadium, keratopatia oczna. Online (access: 30.06.2023).
7. Al-Hity A, Ramaesh K, Lockington D. EDTA chelation for symptomatic band keratopathy: results and recurrence. Eye (Lond). 2018; 32(1): 26-31. http://doi.org/10.1038/eye.2017.264.
8. Jhanji V, Rapuano CJ, Vajpayee RB. Corneal calcific band keratopathy. Curr Opin Ophthalmol. 2011; 22(4): 283-9. http://doi.org/10.1097/ICU.0b013e3283477d36.
9. Narvaez J, Chang M, Ing J et al. Simplified, Readily Available Method for the Treatment of Band Keratopathy With Ethylenediaminetetraacetic Acid. Cornea. 2021; 40(10): 1360-2. http://doi.org/10.1097/ICO.0000000000002635.
10.Kobayashi W, Yokokura S, Hariya T et al. Two percent ethylenediaminetetraacetic acid chelation treatment for band-shaped keratopathy, without blunt scratching after removal of the corneal epithelium. Clin Ophthalmol. 2015; 9: 217-23. http://doi.org/10.2147/OPTH.S75938.
11. Najjar DM, Cohen EJ, Rapuano CJ et al. EDTA chelation for calcific band keratopathy: results and long-term follow-up. Am J Ophthalmol. 2004; 137(6): 1056-64. http://doi.org/10.1016/j.ajo.2004.01.036.
12. Nagpal R, Maharana PK, Roop P et al. Phototherapeutic keratectomy. Surv Ophthalmol. 2020; 65(1): 79-108. http://doi.org/10.1016/j.survophthal.2019.07.002.
13. Wilson SE, Marino GK, Medeiros CS et al. Phototherapeutic Keratectomy: Science and Art. J Refract Surg. 2017; 33(3): 203-10. http://doi.org/10.3928/1081597X-20161123-01.
14. Deshmukh R, Reddy JC, Rapuano CJ et al. Phototherapeutic keratectomy: Indications, methods and decision making. Indian J Ophthalmol. 2020; 68(12): 2856-66. http://doi.org/10.4103/ijo.IJO_1524_20.
15. Wei R, Li M, Yang W et al. Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for Retinoblastoma. Front Med (Lausanne). 2021; 8: 668762. http://doi.org/10.3389/fmed.2021.668762.
16. Qian Y, Zhao P, Li H et al. Transepithelial phototherapeutic keratectomy for the treatment of severe band keratopathy. Int Ophthalmol. 2020; 40(10): 2469-74. http://doi.org/10.1007/s10792-020-01574-3.
17. Sharma N, Mannan R, Sinha R et al. Excimer laser phototherapeutic keratectomy for the treatment of silicone oil-induced band-shaped keratopathy. Eye Contact Lens. 2011; 37(5): 282-5. http://doi.org/10.1097/ICL.0b013e31821269f1.
18. Stewart OG, Morrell AJ. Management of band keratopathy with excimer phototherapeutic keratectomy: visual, refractive, and symptomatic outcome. Eye (Lond). 2003; 17(2): 233-7. http://doi.org/10.1038/sj.eye.6700327.
19. Spadea L, Giannico MI, Iannaccone A et al. Excimer laser-assisted phototherapeutic keratectomies combined to EDTA chelation for the treatment of calcific band keratopathy. Eur J Ophthalmol. 2022; 32(1): NP42-NP46. http://doi.org/10.1177/1120672120969033.