Comparison of drugs belonging to the group of ophthalmic non-steroidal anti-inflammatory drugs Review article

Main Article Content

Alicja Chmura-Hołyst
Kinga Czarnacka
Bartłomiej Żaczek
Ada Pandey
Dominika Prokop
Małgorzata Gawlak
Bartosz Kuźlik
Ismael Alsoubie
Aneta Pyza
Julia Kaczmarek
Katarzyna Sajak-Hydzik
Ilona Pawlicka
Agnieszka Piskorz
Maciej Kozak
Anna Roszkowska

Abstract

Ophthalmic non-steroidal anti-inflammatory drugs are non-steroidal anti-inflammatory drugs used to treat or prevent eye inflammation. Their main action is to relieve symptoms such as pain, redness and swelling that can be caused by eye diseases, injuries or eye surgery. Non-steroidal anti-inflammatory drugs used in ophthalmology include substances such as diclofenac, ketorolac, bromfenac and nepafenac. So far, many studies have been published comparing the effectiveness of various systemic and local non-steroidal anti-inflammatory drugs. This work contains a comparative analysis of the above-mentioned substances in terms of their use and effectiveness in ophthalmology.

Downloads

Download data is not yet available.

Article Details

How to Cite
1.
Chmura-Hołyst A, Czarnacka K, Żaczek B, Pandey A, Prokop D, Gawlak M, Kuźlik B, Alsoubie I, Pyza A, Kaczmarek J, Sajak-Hydzik K, Pawlicka I, Piskorz A, Kozak M, Roszkowska A. Comparison of drugs belonging to the group of ophthalmic non-steroidal anti-inflammatory drugs. Ophthatherapy [Internet]. 2023Dec.31 [cited 2024Apr.27];10(4):277-82. Available from: https://www.journalsmededu.pl/index.php/ophthatherapy/article/view/2941
Section
Conservative treatment

References

1. Kim SJ, Flach AJ, Jampol LM. Nonsteroidal anti-inflammatory drugs in ophthalmology. Surv Ophthalmol. 2010; 55(2): 108-33. http://doi.org/10.1016/j.survophthal.2009.07.005.
2. Wilson DJ, Schutte SM, Abel SR. Comparing the efficacy of ophthalmic NSAIDs in common indications: A literature review to support cost-effective prescribing: A literature review to support cost-effective prescribing. Ann Pharmacother. 2015; 49(6): 727-34. http://doi.org/10.1177/1060028015574593.
3. Kim JM, Shakir O, Adelman RA. A comparison of ketorolac, diclofenac, nevanac, flurbiprofen, and bromfenac in the treatment of cystoid macular edema: a retrospective analysis. Invest Ophthalmol Vis Sci. 2017; 58(8): 4634.
4. Flaxel C, Schain MB, Hamon SC et al. Prospective randomized controlled trial of combination ranibizumab (Lucentis) and bromfenac (Xibrom) for neovascular age-related macular degeneration: a pilot study: A pilot study. Retina. 2012; 32(3): 417-23. http://doi.org/10.1097/IAE.0b013e318229b0af.
5. Gomi F, Sawa M, Tsujikawa M et al. Topical bromfenac as an adjunctive treatment with intravitreal ranibizumab for exudative age-related macular degeneration. Retina. 2012; 32(9): 1804-10. http://doi.org/10.1097/IAE.0b013e31825be87f.
6. Donnenfeld ED, Holland EJ, Stewart RH et al. Bromfenac Ophthalmic Solution 0.09% (Xibrom) Study Group. Bromfenac ophthalmic solution 0.09% (Xibrom) for postoperative ocular pain and inflammation. Ophthalmology. 2007; 114(9): 1653-62. http://doi.org/10.1016/j.ophtha.2006.12.029.
7. Lane SS, Modi SS, Lehmann RP et al. Nepafenac ophthalmic suspension 0.1% for the prevention and treatment of ocular inflammation associated with cataract surgery. J Cataract Refract Surg. 2007; 33(1): 53-8. http://doi.org/10.1016/j.jcrs.2006.08.043.
8. Achiron A, Karmona L, Mimouni M et al. Comparison of the tolerability of diclofenac and nepafenac. J Ocul Pharmacol Ther. 2016; 32(9): 601-5. http://doi.org/10.1089/jop.2016.0057.
9. Szucs PA, Nashed AH, Allegra JR et al. Safety and efficacy of diclofenac ophthalmic solution in the treatment of corneal abrasions. Ann Emerg Med. 2000; 35(2): 131-7. http://doi.org/10.1016/s0196-0644(00)70132-6.
10. Gaynes BI, Fiscella R. Topical nonsteroidal anti-inflammatory drugs for ophthalmic use: A safety review. Drug Saf. 2002; 25(4): 233-50. http://doi.org/10.2165/00002018-200225040-00002.
11. Giannaccare G, Finzi A, Sebastiani S et al. The comparative efficacy and tolerability of diclofenac 0.1% and bromfenac 0.09% ophthalmic solutions after cataract surgery. Curr Eye Res. 2018; 43(12): 1445-53. http://doi.org/10.1080/02713683.2018.1501489.
12. Colin J, Paquette B. Comparison of the analgesic efficacy and safety of nepafenac ophthalmic suspension compared with diclofenac ophthalmic solution for ocular pain and photophobia after excimer laser surgery: a phase II, randomized, double-masked trial. Clin Ther. 2006; 28(4): 527-36. http://doi.org/10.1016/j.clinthera.2006.04.004.
13. Russo A, Costagliola C, Delcassi L et al. Topical nonsteroidal anti-inflammatory drugs for macular edema. Mediators Inflamm. 2013; 2013: 476525. http://doi.org/10.1155/2013/476525.
14. Zhao X, Xia S, Wang E et al. Comparison of the efficacy and patients’ tolerability of Nepafenac and Ketorolac in the treatment of ocular inflammation following cataract surgery: A meta-analysis of randomized controlled trials. PLoS One. 2017; 12(3): e0173254. http://doi.org/10.1371/journal.pone.0173254.
15. Mohammadpour M, Heidari Z, Molani R. Comparison between diclofenac and ketorolac ophthalmic drops for pain management after photorefractive keratectomy: A randomized clinical study: A randomized clinical study. Eye Contact Lens. 2019; 45(2): 137-40. http://doi.org/10.1097/ICL.0000000000000524.
16. Donnenfeld ED, Holland EJ, Durrie DS et al. Double-masked study of the effects of nepafenac 0.1% and ketorolac 0.4% on corneal epithelial wound healing and pain after photorefractive keratectomy. Adv Ther. 2007; 24(4): 852-62. http://doi.org/10.1007/bf02849978.
17. Trattler W, McDonald M. Double-masked comparison of ketorolac tromethamine 0.4% versus nepafenac sodium 0.1% for postoperative healing rates and pain control in eyes undergoing surface ablation. Cornea. 2007; 26(6): 665-9. http://doi.org/10.1097/ICO.0b013e31805290ce.
18. Vetrugno M, Maineo A, Quaranta GM et al. A randomized, double-masked, clinical study of the efficacy of four nonsteroidal anti-inflammatory drugs in pain control after excimer laser photorefractive keratectomy. Clin Ther. 2000; 22(6): 719-31. http://doi.org/10.1016/s0149-2918(00)90006-7.
19. Rajpal RK, Ross B, Rajpal S et al. Bromfenac ophthalmic solution for the treatment of postoperative ocular pain and inflammation: safety, efficacy, and patient adherence. Patient Prefer Adherence. 2014; 925. http://doi.org/10.2147/ppa.s46667.
20. Walters TR, Goldberg DF, Peace JH et al. Bromfenac Ophthalmic Solution 0.07% Once Daily Study Group. Bromfenac ophthalmic solution 0.07% dosed once daily for cataract surgery: results of 2 randomized controlled trials. Ophthalmology. 2014; 121(1): 25-33. http://doi.org/10.1016/j.ophtha.2013.07.006.
21. Silverstein SM. Bromfenac Ophthalmic Solution 0.07% Versus Nepafenac Ophthalmic Suspension 0.3% for Post-Cataract Surgery Inflammation: A Pilot Study of Identical Dosing Regimens with Pre-Surgical “Pulse” Dose. Ophthalmol Ther. 2019; 8(4): 577-87. http://doi.org/10.1007/s40123-019-00215-y.
22. Chinchurreta Capote AM, Lorenzo Soto M, Rivas Ruiz F et al. Comparative study of the efficacy and safety of bromfenac, nepafenac and diclofenac sodium for the prevention of cystoid macular edema after phacoemulsification. Int J Ophthalmol. 2018; 11(7): 1210-6. http://doi.org/10.18240/ijo.2018.07.22.
23. Modi SS, Lehmann RP, Walters TR et al. Once-daily nepafenac ophthalmic suspension 0.3% to prevent and treat ocular inflammation and pain after cataract surgery: phase 3 study. J Cataract Refract Surg. 2014; 40(2): 203-11. http://doi.org/10.1016/j.jcrs.2013.07.042.
24. Cagini C, Pellegrino A, Cerquaglia A et al. Comparison of the effect of diclofenac 0.1% and nepafenac 0.1% on aqueous flare in patients undergoing cataract surgery: A prospective randomized study. Curr Eye Res. 2020; 45(9): 1089-93. http://doi.org/10.1080/02713683. 2020.1725061.
25. Kim S, Schoenberger S. Zastosowanie niesteroidowych leków przeciwzapalnych w chorobach siatkówki. Okulistyka po Dyplomie. 2013; 3(2): 46-55.
26. Alnagdy A, Eissa AM, El-Kannishy A. Topical NSAIDs in Prevention of Postcataract Macular Edema. Frontiers in Ophthalmology and Ocular Imaging. 2019. http://doi.org/10.5772/intechopen.82321.
27. Medycyna Praktyczna.
28. Wielka Baza ChPL.