The effect of atropine 0.025% on optical quality, corneal tomography, and binocular vision Original research study
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Abstract
Purpose: Our study pointed to evaluate the effect of atropine eye drop at 0.025% on optical quality, corneal tomography, and binocular vision.
Methods: A total of 51 university students received 0.025% atropine eye drops, once nightly to both eyes for 5 nights. Refraction, visual acuity (VA), accommodation facility, accommodation lag, near point of convergence (NPC), near point of accommodation (NPA), heterophoria, and corneal topography were measured before and after instillation.
Results: After using 0.025% atropine eye drops, the far and near heterophoria changed from -1.73 (±0.415) to -0.82 (±0.267) (p = 0.005) and -3.69 (±0.823) to 0.018 (±0.726) (p <0.001), NPC increased from 4.573 (±0.4763) to 6.625 (±0.8328) (p = 0.002), NPA increased from OD (right eye) = 11.014 (±0.4059) to 17.635 (±1.0303) (p <0.001), and OS (left eye) = 10.867 (±0.4394) to 17.110 (±0.9679) (p <0.001), Monocular estimated method (MEM) retinoscopy increased from OD = 0.848 (±0.0415) to 1.137 (±0.0570) (p <0.001), and OS = 0.892 (±0.0439) to 1.196 (±0.0570) (p <0.001), accommodation facility decreased from OD = 9.69 (±0.827) to 8.44 (±0.878) (p = 0.119), and OS = 11.01 (±0.983) to 8.69 (±0.899) (p = 0.005), near VA decreased from OD = 0.992 (±0.0055) to 0.937 (±0.0170) (p = 0.004), and OS = 0.992 (±0.0055) to 0.927 (±0.0219) (p = 0.005), pupil diameter increased from OD = 3.043 (±0.0783) to 5.121 (±0.1314) (p <0.001), and OS = 3.059 (±0.0714) to 5.253 (±0.1412) (p <0.001), far VA, central corneal thickness (CCT), corneal densitometry, corneal curvature, ocular and corneal higher order aberration (HOA) and lower order aberration (LOA) remained unchanged (all p >0.05).
Conclusions: The far and near VA, monocular accommodation facility, spherical refraction, corneal densitometry, corneal curvature, CCT, ocular and corneal HOA and LOA did not change significantly, but heterophoria, NPC, NPA, accommodative lag and pupil size changed significantly after instillation
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Copyright: Medical Education sp. z o.o. License allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Address reprint requests to: Medical Education, Marcin Kuźma (marcin.kuzma@mededu.pl)
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