Bridging haematology and cardiology: recurrent ST-segment elevation myocardial infarction in a patient with multiple myeloma Opis przypadku

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Wiktoria Michnowska
Aleksandra Liżewska-Springer
Agata Tyczyńska
Marta Marcinkowska
Agnieszka Mickiewicz
Ewa Lewicka

Abstrakt

We present case of a 49-year-old man with arterial hypertension, hypercholesterolemia, and nephrotic
syndrome was diagnosed with multiple myeloma, who underwent first-line treatment with the DVTd
regimen. This case highlights the complex interplay between multiple myeloma, prothrombotic anticancer
therapy, and severe dyslipoproteinemia in accelerating coronary atherosclerosis and recurrent
ischemic events.

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Dział
CARDIO-ONCOLOGY

Bibliografia

1. Zangari M, Saghafifar F, Mehta P. The blood coagulation mechanism in multiple myeloma. Semin Thromb Hemost. 2003; 29(3): 275-82. https://doi.org/10.1055/s-2003-40965.
2. Kronenberg F, Mora S, Stroes ESG et al. Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement. Eur Heart J. 2022; 43(39): 3925-46. https://doi.org/10.1093/eurheartj/ehac361.
3. Nicholls SJ. PCSK9 inhibitors and reduction in cardiovascular events: Current evidence and future perspectives. Kardiol Pol. 2023; 81(2): 115-22. https://doi.org/10.33963/KP.a 2023.0030.
4. Ochotnicka J, Nowak J, Kowalski P et al. Measurement of lipoprotein(a) levels in real-world clinical and laboratory settings: A single-center experience. Pol Arch Intern Med. 2024; 134(11): 16891. https://doi.org/10.20452/pamw.16891.
5. Corso A, Lorenzi A, Terulla V et al. Modification of thrombomodulin plasma levels in refractory myeloma patients during treatment with thalidomide and dexamethasone. Ann Hematol. 2004; 83(9): 588-591. https://doi.org/10.1007/s00277-004-0891-6.