Reasons for using simetikon Review article
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Published:
Mar 31, 2017
Keywords:
flatulence, antibiotics, statins, bile acid sequestrants, orlistat, acarbose, metformin, SSRI, acetylsalicylic acid, incretin drugs, sartans, ACE-inhibitors, Ca-blockers
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Abstract
The flatulence is a gastrointestinal tract disorder consisting of gas accumulation. It manifests as discomfort in the abdominal cavity and so called “gas-drop” which significantly reduces the quality of life, and in addition is not socially acceptable. This article presents actual knowledge on drugs, which can cause clinically significant flatulence, and also analyzes the influence of incretin drugs – a new group of antidiabetic drugs – on the function of the gastrointestinal tract. Based on the presented data it seems that in most cases the flatulence is not a clinical problem but rather a problem which negatively affect the life.
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How to Cite
Krząścik, P., Knypl, K., & Łabuzek, K. (2017). Reasons for using simetikon. Medycyna Faktow (J EBM), 10(1(34), 47-51. Retrieved from https://www.journalsmededu.pl/index.php/jebm/article/view/2194
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10. Muscari A., Puddu G.M., Puddu P.: Lipid-lowering drugs: are adverse effects predictable and reversible? Cardiology 2002; 97: 115-121.
11. Trindade E., Menon D., Topfer L.A., Coloma C.: Adverse effects associated with selective serotonin reuptake inhibitors and tricyclic antidepressants: a meta-analysis. CMAJ 1998; 159: 1245-1252.
12. Focks J.J., Tielemans M.M., van Rossum L.G. et al.: Gastrointestinal symptoms in low-dose aspirin users: a comparison between plain and buffered aspirin. Neth. Heart J. 2014; 22: 107-112.
13. Gu J., Meng X., Guo Y. et al.: The efficacy and safety of liraglutide added to metformin in patients with diabetes: a metaanalysis of randomized controlled trials. Sci. Rep. 2016; 6: 32714. DOI: 10.1038/srep32714.
14. Smits M.M., Tonneijck L., Muskiet M.H.A. et al.: Cardiovascular, renal and gastrointestinal effects of incretin-based therapies: an acute and 12-week randomised, double-blind, placebo-controlled, mechanistic intervention trial in type 2 diabetes. BMJ Open 2015; 5:e009579. DOI: 10.1136/bmjopen-2015-009579.
15. Russell S.: Incretin-based therapies for type 2 diabetes mellitus: a review of direct comparisons of efficacy, safety and patient satisfaction. Int. J. Clin. Pharm. 2013; 35: 159-172.
16. Blonde L., Montanya E.: Comparison of liraglutide versus other incretin-related anti-hyperglycaemic agents. Diabetes Obes. Metab. 2012; 14(supl. 2): 20-32.
17. Schwartz S., Fonseca V., Berner B.: Efficacy, tolerability, and safety of a novel once-daily extended-release metformin in patients with type 2 diabetes. Diabetes Care. 2006; 29(4): 759-764.
18. Bronner F.: Mechanisms of intestinal calcium absorption. J. Cell. Biochem. 2003; 88: 387-393.
19. Aljada A., Mousa S.A.: Metformin and neoplasia: implications and indications. Pharmacol. Ther. 2012; 133: 108-115.
20. Gong Z., Aragaki A.K., Chlebowski R.T.: Diabetes, metformin and incidence of and death from invasive cancer in postmenopausal women: results from the Women’s Health Initiative. Int. J. Cancer 2016; 138(8): 1915-1927.
21. Chen H.P., Shieh J.J., Chang C.C. et al.: Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies. Gut. 2013; 62(4): 606-615.
22. Sweetman S.C.: Martindale. The Complete Drug Reference, 32nd ed. Pharmaceutical Press 2002.
23. Podlewski J., Chwalibogowska-Podlewska A.: Leki współczesnej terapii. Wydanie XIX. Medical Tribune Polska, Warszawa 2009.
24. Kostowski W., Herman Z.S.: Farmakologia. Podstawy farmakoterapii. Podręcznik dla studentów medycyny i lekarzy. Wydanie III. Wydawnictwo Lekarskie PZWL, Warszawa 2003.
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