Challenges in the treatment of Helicobacter pylori infection: what’s new after Maastricht VI Review article
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Published:
Oct 20, 2026
Keywords:
eradication, Helicobacter pylori, probiotics
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Abstract
The article presents an overview of current reports on Helicobacter pylori eradication, as well as the principles of using probiotics to improve treatment efficacy and reduce the risk of adverse effects.
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How to Cite
Gąsiorowska, A. (2026). Challenges in the treatment of Helicobacter pylori infection: what’s new after Maastricht VI. Medycyna Faktow (J EBM), 19(2(71), 170-173. https://doi.org/10.24292/01.MF.0226.4
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References
1. Malfertheiner P, Megraud P, Rokkas T et al. Management of Helicobacter pylori infection: the Maastricht VI/Florence consensus report. Gut. 2022; 71: 1724-62.
2. Jaroń K, Pietrzak A, Daniluk J et al. Diagnostic and therapeutic recommendations on Helicobacter pylori infection. Recommendations of the Working Group of the Polish Society of Gastroenterology. Gastroenterology Rev. 2023; 18(3): 225-48.
3. Olmedo L, Calvet X, Gene E et al. Evolution of the use, effectiveness and safety of bismuth-containing quadruple therapy for Helicobacter pylori infection between 2013 and 2021: results from the European registry on H. pylori management (Hp-EuReg). Gut. 2024; 74(1): 15-25.
4. Nyssen OP, Montes N, Perez-Aisa A et al. Effectiveness and Safety of First-Line Non-Bismuth Quadruple Concomitant Therapy Versus Single- Capsule Bismuth Quadruple Therapy. Aliment Pharmacol Therap. 2025; 62: 809-20.
5. Martinez-Domingues SJ, Lanas A, Ceamanos E et al. Higher Doses of Bismuth and Antibiotics Do Not Improve Helicobacter pylori Treatment Effectiveness: Results From European Registry on Helicobacter pylori Management. Clin Gastroenterol Hepatol. 2026; 0.
6. Yuan L, Yang C, Han Y et al. Beyond antibiotics: probiotics as a promising ally against Helicobacter pylori. Front Pharmacol. 2025; 16: 1620870.
7. Deza DC, Alcedo J, Lafuente M et al. Probiotics Prescribed With Helicobacter pylori Eradication Therapy in Europe: Usage Pattern, Effectiveness, and Safety. Results From the European Registry on Helicobacter pylori Management (Hp-EuReg). Am J Gastroenterol. 2025; 120: 2644-59.
8. Nyssen OP, Jonaitis L, Perez-Aisa A et al. Real-World Effectiveness and Safety of Saccharomyces boulardii CNCM I-745 as Adjunct Therapy for Helicobacter pylori Eradication: Data From the European Registry on H. pylori Management (Hp- EuReg). Helicobacter. 2026; 31: e70119.
9. Yang Z, Zhou Y, Han Z et al. The effects of probiotics supplementation on Helicobacter pylori standard treatment: an umbrella review of systematic reviews with meta analyses. Sci Rep. 2024; 14: 10069.
10. Banasiewicz T, Domagalska D, Borycka-Kiciak K et al. Determination of butyric acid dosage based on clinical and experimental studies – a literature review. Gastroenterology Rev. 2020; 15(2): 119-25.
2. Jaroń K, Pietrzak A, Daniluk J et al. Diagnostic and therapeutic recommendations on Helicobacter pylori infection. Recommendations of the Working Group of the Polish Society of Gastroenterology. Gastroenterology Rev. 2023; 18(3): 225-48.
3. Olmedo L, Calvet X, Gene E et al. Evolution of the use, effectiveness and safety of bismuth-containing quadruple therapy for Helicobacter pylori infection between 2013 and 2021: results from the European registry on H. pylori management (Hp-EuReg). Gut. 2024; 74(1): 15-25.
4. Nyssen OP, Montes N, Perez-Aisa A et al. Effectiveness and Safety of First-Line Non-Bismuth Quadruple Concomitant Therapy Versus Single- Capsule Bismuth Quadruple Therapy. Aliment Pharmacol Therap. 2025; 62: 809-20.
5. Martinez-Domingues SJ, Lanas A, Ceamanos E et al. Higher Doses of Bismuth and Antibiotics Do Not Improve Helicobacter pylori Treatment Effectiveness: Results From European Registry on Helicobacter pylori Management. Clin Gastroenterol Hepatol. 2026; 0.
6. Yuan L, Yang C, Han Y et al. Beyond antibiotics: probiotics as a promising ally against Helicobacter pylori. Front Pharmacol. 2025; 16: 1620870.
7. Deza DC, Alcedo J, Lafuente M et al. Probiotics Prescribed With Helicobacter pylori Eradication Therapy in Europe: Usage Pattern, Effectiveness, and Safety. Results From the European Registry on Helicobacter pylori Management (Hp-EuReg). Am J Gastroenterol. 2025; 120: 2644-59.
8. Nyssen OP, Jonaitis L, Perez-Aisa A et al. Real-World Effectiveness and Safety of Saccharomyces boulardii CNCM I-745 as Adjunct Therapy for Helicobacter pylori Eradication: Data From the European Registry on H. pylori Management (Hp- EuReg). Helicobacter. 2026; 31: e70119.
9. Yang Z, Zhou Y, Han Z et al. The effects of probiotics supplementation on Helicobacter pylori standard treatment: an umbrella review of systematic reviews with meta analyses. Sci Rep. 2024; 14: 10069.
10. Banasiewicz T, Domagalska D, Borycka-Kiciak K et al. Determination of butyric acid dosage based on clinical and experimental studies – a literature review. Gastroenterology Rev. 2020; 15(2): 119-25.