Czy istnieje krzywa J dla rozkurczowego ciśnienia tętniczego? Artykuł przeglądowy

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Piotr Sobieraj
Jacek Lewandowski
Maciej Siński

Abstrakt

Hipoteza krzywej J związana ze wzrostem ryzyka zdarzeń sercowo-naczyniowych także przy zbyt niskich wartościach ciśnienia tętniczego pojawiła się w medycynie pod koniec XX w. Podstawę patofizjologiczną stanowi zależność przepływu wieńcowego od rozkurczowego ciśnienia tętniczego. Aktualnie zalecane niższe docelowe wartości ciśnienia tętniczego podczas leczenia nadciśnienia tętniczego (NT) mogą się wiązać z nadmierną redukcją rozkurczowego ciśnienia tętniczego, a temat krzywej J powraca jako jeden z ważniejszych w leczeniu NT. Obecnie istnieją dowody naukowe opierające się na analizach post-hoc dużych randomizowanych badań, świadczące o niekorzystnym wpływie nadmiernej redukcji rozkurczowego ciśnienia tętniczego w szczególności w grupie osób z chorobą sercowo-naczyniową. W artykule przedstawiono dane dotyczące zbyt niskiego ciśnienia rozkurczowego w różnych populacjach chorych.

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Sobieraj , P., Lewandowski , J., & Siński , M. (2018). Czy istnieje krzywa J dla rozkurczowego ciśnienia tętniczego?. Kardiologia W Praktyce, 12(3-4), 37-46. Pobrano z https://www.journalsmededu.pl/index.php/kwp/article/view/1212
Dział
Dowody medyczne w kardiologii

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