Avoiding Cardiovascular Events through Combination Therapy in Patients Living with Systolic Hypertension Review article

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Piotr Jędrusik

Abstract

The ACCOMPLISH study compared combined treatment with benazepril-amlodypine and benazepril-hydrochlorthiazide in hypertensive patients at high risk of cardiovascular events. The use of benazepril-amlodipine combination resulted in reduced cardiovascular morbidity and mortality compared to treatment with benazepril and hydrochlorthiazide despite similar blood pressure reduction in both study groups.

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How to Cite
Jędrusik , P. (2009). Avoiding Cardiovascular Events through Combination Therapy in Patients Living with Systolic Hypertension. Cardiology in Practice, 3(1), 23-25. Retrieved from https://www.journalsmededu.pl/index.php/kwp/article/view/1667
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References

1. Jamerson K., Weber M.A., Bakris G.L. et al.: Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N. Engl. J. Med. 2008, 359: 2417-2428.
2. Chobanian A.V.: Does it matter how hypertension is controlled? N. Engl. J. Med. 2008, 359: 2485-88.
3. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group: Major outcomes in high-risk hypertensive patients randomized to angiotensin converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002, 288: 2981-2997.