10 powodów, dla których warto zastosować peryndopryl w leczeniu nadciśnienia tętniczego Artykuł przeglądowy

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Justyna Pordzik
Marek Postuła

Abstrakt

Inhibitory enzymu konwertującego angiotensynę (ACE) stanowią heterogenną grupę leków, która różni się wpływem klinicznym na pacjenta wynikającym z różnic dotyczących lipofilności, wiązania z tkankowym ACE, czasem działania, okresu połowicznego rozpadu oraz wpływu na stężenie bradykininy. Spośród inhibitorów ACE peryndopryl cechuje się unikalnymi właściwościami plejotropowymi, które są związane z selektywnością w stosunku do miejsc wiążących bradykininę oraz działaniem na syntezę tlenku azotu i apoptozę komórek śródbłonka.

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Pordzik , J., & Postuła , M. (2017). 10 powodów, dla których warto zastosować peryndopryl w leczeniu nadciśnienia tętniczego . Kardiologia W Praktyce, 11(1), 8-11. Pobrano z https://www.journalsmededu.pl/index.php/kwp/article/view/1254
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